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Proteintech
GPD1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
13451-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
GPD1 Fusion Protein Ag4278 (1-349 aa encoded by BC032234)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.33 mg/mL
规格
49.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MASKKVCIV GSGNWGSAIA KIVGGNAAQL AQFDPRVTMW VFEEDIGGKK LTEIINTQHE NVKYLPGHKL PPNVVAVPDV VQAAEDADIL IFVVPHQFIG KICDQLKGHL KANATGISLI KGVDEGPNGL KLISEVIGER LGIPMSVLMG ANIASEVADE KFCETTIGCK DPAQGQLLKE LMQTPNFRIT VVQEVDTVEI CGALKNVVAV GAGFCDGLGF GDNTKAAVIR LGLMEMIAFA KLFCSGPVSS ATFLESCGVA DLITTCYGGR NRKVAEAFAR TGKSIEQLEK ELLNGQKLQG PETARELYSI LQHKGLVDKF PLFMAVYKVC YEGQPVGEFI HCLQNHPEHM (1-349 aa encoded by BC032234)
靶标信息
This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: epididymis secretory sperm binding protein; glycerol 3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1 (soluble); glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic; glycerolphosphate dehydrogenase 1, cytoplasmic adult; glycerophosphate dehydrogenase; GPD-C; GPDH-C; unnamed protein product
基因别名: Gdc-1; Gdc1; GPD-C; Gpd3; GPDH; GPDH-C; HTGTI
UniProt ID: (Human) P21695, (Rat) O35077, (Mouse) P13707
Entrez Gene ID: (Human) 2819, (Rat) 60666, (Mouse) 14555
carbohydrate metabolic process
glycerol-3-phosphate metabolic process
glycerol-3-phosphate catabolic process
gluconeogenesis
glycerophosphate shuttle
positive regulation of glycolytic process
glycerolipid metabolic process
cellular response to cAMP
cellular response to tumor necrosis factor
NAD metabolic process
glyceraldehyde-3-phosphate biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
