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Invitrogen
GPR177 Polyclonal Antibody
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GPR177 Antibody (PA5-98483) in IHC (P)
Immunohistochemical analysis of GPR177 in paraffin embedded human adrenal gland tissue using a GPR177 polyclonal antibody (Product # PA5-98483) at a dilution of 1:200. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary... View More
产品信息
PA5-98483
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
C. elegans,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Protein wntless homolog protein (123-232AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins. Plays also an important role in establishment of the anterior-posterior body axis formation during development. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: EVI; G protein-coupled receptor 177; Integral membrane protein GPR177; Protein evenness interrupted homolog; Protein wntless homolog; Putative NF-kappa-B-activating protein 373; putative NFkB activating protein 373
基因别名: C1orf139; EVI; GPR177; mig-14; MRP; UNQ85/PRO18667; WLS
UniProt ID: (Human) Q5T9L3
Entrez Gene ID: (Human) 79971
mesoderm formation
intracellular protein transport
anterior/posterior axis specification
Wnt signaling pathway
positive regulation of Wnt signaling pathway
midbrain development
hindbrain development
exocrine pancreas development
positive regulation of I-kappaB kinase/NF-kappaB signaling
Wnt protein secretion
positive regulation of Wnt protein secretion
positive regulation of canonical Wnt signaling pathway
