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Invitrogen
GPR37 Polyclonal Antibody
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产品信息
PA5-65344
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human GPR37
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: RWKGARGQEPS ETLGRGNPTA LQLFLQISEE EEKGPRGAGI SGRSQEQSVK TVPGASDLFY WPRRAGKLQG SHHKPLSKTA NGLAGHEGWT IALPGRALAQ NGSLGEGIHE PGGPRRGNST NRRVRLKNPF YPLTQESYGA
Highest antigen sequence identity to the following orthologs - mouse 59%, rat 62%.
靶标信息
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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