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Invitrogen
GPR37 (extracellular) Polyclonal Antibody
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GPR37 (extracellular) Antibody (PA5-111837) in WB
Western Blot analysis of GPR37 was performed in mouse (lanes 1 and 3) and rat (lanes 2 and 4) brain lysates. Lane 1,2: GPR37 (extracellular) Antibody (Product # PA5-111837) at a dilution of 1:200. Lane 3,4: GPR37 (extracellular) Antibody preincubated with the negative control antigen.
产品信息
PA5-111837
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to amino acid residues 234-247 of rat GPR37 (Extracellular, N-terminus)
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
产品详细信息
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: (C)RVRLKNP FYPLTQE
Homology: Mouse, human amino acid residues are identical.
靶标信息
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function. Panneuronal expression of Parkin substrate Pael-R causes age-dependent selective degeneration of Drosophila dopaminergic (DA) neurons; coexpression of Parkin degrades Pael-R and suppresses its toxicity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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