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Invitrogen
GPR83 Polyclonal Antibody
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产品信息
PA5-142839
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-RRYGAESQNPTVK (aa 59-71).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Additional Information: The immunizing peptide represents part of an extracellular domain.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
靶标信息
GPR83, a 423 A.A protein, is an orphan member of GPCR protein family and is closely related to tachykinin and NPY receptors. It is a human homolog of mouse GIR protein and is exclusively expressed and selectively up-regulated in brain. It is a cell surface receptor protein consisting of a putative seven-transmembrane-domain. Reports suggest GPR83 might be involved in the regulation of immune tolerance mechanism by inducing peripheral generation of Foxp3+ Treg cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: G protein-coupled receptor 72; G-protein coupled receptor 72; G-protein coupled receptor 83; glucocorticoid induced receptor; Glucocorticoid-induced receptor; Hcepto9; Jp05; probable G-protein coupled receptor 83
基因别名: AW045253; GIR; GPR72; GPR83; JP05; KIAA1540; RP105; RP39; RP82
UniProt ID: (Human) Q9NYM4, (Mouse) P30731, (Rat) Q8VHD7
Entrez Gene ID: (Human) 10888, (Mouse) 14608, (Rat) 140595
