Invitrogen

GRASP1 Polyclonal Antibody

Name: GRASP1 Polyclonal Antibody
Brand: Invitrogen
SKU: PA1-4662
Availability: InStock

查看其他14个GRASP1抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

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GRASP1 Antibody (PA1-4662) in WB

Western blot of GRASP1 in rat cerebellar lysate showing the specific immunolabeling of a band at ~95 kDa corresponding to GRASP1 polyclonal antibody (Product # PA1-4662).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image GRASP1 Polyclonal Antibody

产品信息

PA1-4662

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

产品规格

种属反应

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide corresponding to the C-terminal region of rat GRIPAP1 conjugated to KLH

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.25 mg/mL

25 µg

纯化类型

Affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

no preservative

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2232581

产品详细信息

This antibody is predicted to react with bovine, canine, human and mouse based on 100% sequence homology.

This antibody is specific for the ~95 kDa GRASP protein.

靶标信息

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).

仅用于科研。不用于诊断过程。未经明确授权不得转售。