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Invitrogen
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Immunogen sequence: LPVGRIEEPF WQNFKHLQEE VFQKIKTLAQ LSKDVQDVMF YSILAMLRDR GALQDLMNML ELDSSGHLDG PGGAILKKLQ QDSNHAWFNP KDP
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 53%.
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Gasdermin-C; melanoma-derived leucine zipper, extra-nuclear factor; Melanoma-derived leucine zipper-containing extranuclear factor
基因别名: GSDMC; MLZE
UniProt ID: (Human) Q9BYG8
Entrez Gene ID: (Human) 56169