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Invitrogen
GTF2E1 Polyclonal Antibody
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产品信息
PA5-90339
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 230-439 of human GTF2E1 (NP_0055042)
偶联物
形式
Liquid
浓度
2.82 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LAGGHHREAW ATKGPSYEDL YTQNVVINMD DQEDLHRASL EGKSAKERPI WLRESTVQGA YGSEDMKEGG IDMDAFQERE EGHAGPDDNE EVMRALLIHE KKTSSAMAGS VGAAAPVTAA NGSDSESETS ESDDDSPPRP AAVAVHKREE DEEEDDEFEE VADDPIVMVA GRPFSYSEVS QRPELVAQMT PEEKEAYIAM GQRMFEDLFE; Positive Samples: HeLa, Jurkat, A-431, Mouse brain, Mouse spleen, Mouse testis; Cellular Location: Nucleus
靶标信息
The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits of relative molecular mass 57, 000 (TFIIE-alpha) and 34, 000 (TFIIE-beta) and joins the preinitiation complex after RNA polymerase II and TFIIF. TFIIE-alpha is necessary for transcription initiation together with TFIIE-beta, and recombinant TFIIE-alpha can fully replace the natural subunit in an in vitro transcription assay. Its sequence contains several interesting structural motifs (leucine repeat, zinc finger and helix-turn-helix) and sequence similarities to bacterial sigma factors that suggest direct involvement in the regulation of transcription initiation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: general transcription factor II E, polypeptide 1 (alpha subunit, 56kDa); General transcription factor IIE 56 kDa subunit; General transcription factor IIE subunit 1; general transcription factor IIE, polypeptide 1 (alpha subunit); general transcription factor IIE, polypeptide 1 (alpha subunit, 56kDa); general transcription factor IIE, polypeptide 1, alpha 56kDa; TFIIE alpha subunit; TFIIE-alpha; Transcription initiation factor IIE subunit alpha
基因别名: 2610024P03Rik; 56kDa; AI303800; FE; GTF2E1; TF2E1; TFIIE-A
UniProt ID: (Human) P29083, (Mouse) Q9D0D5
Entrez Gene ID: (Human) 2960, (Rat) 303918, (Mouse) 74197
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
viral process
snRNA transcription from RNA polymerase II promoter
biological_process
transcription, DNA-templated
