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Invitrogen
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Peptide sequence: QALAEKVKEA ERDVSLTSLA KLPSETIFVG CEFLHHLLRE WGEELQAVLR
Sequence homology: Cow: 92%; Dog: 100%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies. The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Component of gems 4; DKFZp434B131; DKFZp434D174; Gem-associated protein 4; Gemin-4; HCC-associated protein 1; p97
基因别名: GEMIN4; HC56; HCAP1; HHRF-1; p97
UniProt ID: (Human) P57678
Entrez Gene ID: (Human) 50628