Bioss

GluR1, GluR2 Polyclonal Antibody

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说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持
说明书
实验方案
问题与答案
技术支持

产品信息

BS-10042R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:500-1:2,000
-

免疫组化（石蜡） (IHC (P))

1:200
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:100-1:500
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human GluR1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: AMPA 1; AMPA selective glutamate receptor; AMPA-selective glutamate receptor 1; AMPA-selective glutamate receptor 2; GluA1; GluR-1; GluR-2; GluR-A; GluR-B; GluR-K1; GluR-K2; GluR1; Glutamate receptor 1; Glutamate receptor 2; glutamate receptor A; glutamate receptor B; glutamate receptor B flip isoform; Glutamate receptor ionotropic, AMPA 1; Glutamate receptor ionotropic, AMPA 2; glutamate receptor subunit GluR1; glutamate receptor, ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA1 (alpha 1)

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基因别名: 2900051M01Rik; Glr-1; Glr1; GLUA1; GluA2; GLUH1; Glur-1; Glur-2; GluR-A; GluR-B; gluR-K1; GluR-K2; GLUR1; GLUR2; GLURA; GLURB; GRIA1; GRIA2; HBGR1; HBGR2; HIPA1

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UniProt ID: (Human) P42261, (Human) P42262, (Rat) P19490, (Mouse) P23818, (Rat) P19491

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Entrez Gene ID: (Human) 2890, (Human) 2891, (Rat) 50592, (Mouse) 14799, (Mouse) 14800, (Rat) 29627

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功能
AMPA glutamate receptor activity excitatory extracellular ligand-gated ion channel activity extracellular-glutamate-gated ion channel activity protein binding glutamate receptor activity PDZ domain binding ionotropic glutamate receptor activity G-protein alpha-subunit binding adenylate cyclase binding protein kinase binding protein domain specific binding small GTPase binding myosin V binding G-protein beta-subunit binding beta-2 adrenergic receptor binding identical protein binding protein homodimerization activity protein kinase A binding receptor activity ion channel activity kainate selective glutamate receptor activity calcium channel regulator activity transmembrane signal receptor
参与通路
ER to Golgi vesicle-mediated transport signal transduction chemical synaptic transmission long-term memory receptor internalization ion transmembrane transport ionotropic glutamate receptor signaling pathway COPII vesicle coating long term synaptic depression regulation of receptor recycling response to toxic substance response to lithium ion response to organic cyclic compound neuronal action potential spinal cord development response to estradiol synaptic transmission, glutamatergic response to cocaine response to drug response to peptide hormone positive regulation of membrane potential response to arsenic-containing substance regulation of synaptic plasticity modulation of synaptic transmission positive regulation of synaptic transmission response to electrical stimulus response to fungicide cellular response to amino acid stimulus cellular response to dsRNA cellular response to growth factor stimulus cellular response to peptide hormone stimulus cellular response to organic cyclic compound cellular response to amine stimulus transport ion transport establishment of protein localization protein tetramerization regulation of synaptic transmission, glutamatergic
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