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Invitrogen
Granzyme K Monoclonal Antibody (GM26E7)
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Granzyme K Antibody (MA1-17754) in Flow
Flow cytometry analysis of Granzyme K in BOSC23 cells using a Granzyme K Monoclonal Antibody (Product # MA1-17754) at a 1.2 µg/10^6 cells dilution, detected with a PE-conjugated secondary antibody, as shown in red. Isotype control antibody is shown in black.
产品信息
MA1-17754
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GM26E7
抗原
cDNA encoding human Granzyme K
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.
This antibody can be used in a Sandwich ELISA as a capture antibody with Product # MA1-17755 as a detection antibody.
靶标信息
Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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