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Abnova
HCN4 Monoclonal Antibody (2A5)
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产品信息
H00010021-M04
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2A5
抗原
HCN4 (NP_005468.1, 1105 a.a. approximately 1203 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: SPHSSGESMA AFPLFPRAGG GSGGSGSSGG LGPPGRPYGA IPGQHVTLPR KTSSGSLPPP LSLFGARATS SGGPPLTAGP QREPGARPEP VRSKLPSNL
靶标信息
HCN4 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. It has been shown that HCN4 channels function as receptors for sour taste, and are associated with pacemaker potential generation in the sinoatrial node.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hyperpolarization activated cyclic nucleotide-gated cation channel 4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
基因别名: HCN4; SSS2
UniProt ID: (Human) Q9Y3Q4
Entrez Gene ID: (Human) 10021
regulation of heart rate
regulation of membrane depolarization
cation transport
muscle contraction
blood circulation
regulation of ion transmembrane transport
sodium ion transmembrane transport
regulation of membrane potential
regulation of cardiac muscle contraction
regulation of postsynaptic membrane potential
cellular response to cAMP
cellular response to cGMP
potassium ion transmembrane transport
SA node cell action potential
regulation of heart rate by cardiac conduction
