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Abnova
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Sequence of this protein is as follows: MGFCFFNSVA IACRQLQQQS KASKILIVDW DVHHGNGTQQ TFYQDPSVLY ISLHRHDDGN FFPGSGAVDE VGAGSGEGFN VNVAWAGGLD PPMGDPEYLA AFRIVVMPIA REFSPDLVLV SAGFDAAEGH PAPLGGYHVS AKCFGYMTQQ LMNLAGGAVV LALEGGHDLT AICDASEACV AALLGNRVDP LSEEGWKQKP NLNAIRSLEA VIRVHSKYWG CMQRLASCPD SWVPRVPGAD KEEVEAVTAL ASLSVGILAE DRPSEQLVEE EEPMNL
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。