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OriGene
HDGF Monoclonal Antibody (OTI8C7), TrueMAB™
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HDGF Antibody (CF808926) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HDGF (RC204148, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HDGF. (1. Positive lysates LY417948 (100 µg) and LC417948 (20 µg) can be purchased separately from OriGene.
产品信息
CF808926
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI8C7
抗原
Full length human recombinant protein of human HDGF produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
HDGF is a member of the hepatoma-derived growth factor family. This protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686J1764; FLJ96580; HDGF; Hepatoma-derived growth factor; High mobility group protein 1-like 2; HMG-1L2
基因别名: AI118077; D3Ertd299e; HDGF; HMG1L2; Tdrm1
UniProt ID: (Human) P51858, (Rat) Q8VHK7, (Mouse) P51859
Entrez Gene ID: (Human) 3068, (Rat) 114499, (Mouse) 15191
nucleotide binding
RNA polymerase II transcription corepressor activity
transcription corepressor binding
DNA binding
growth factor activity
heparin binding
poly(A) RNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
protein binding
transcription cofactor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
signal transduction
cell proliferation
IRE1-mediated unfolded protein response
cellular process
protein localization to nucleus
positive regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
