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Proteintech
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Immunogen sequence: VMEGMDKET FEFKFGKELT FTTVLSDQQV VELIPGGAGI VVGYGDRSRF IQLVQKARLE ESKEQVAAMQ AGLLKVVPQA VLDLLTWQEL EKKVCGDPEV TVDALRKLTR FEDFEPSDSR VQYFWEALNN FTNEDRSRFL RFVTGRSRLP ARIYIYPDKL GYETTDALPE SSTCSSTLFL PHYASAKVCE EKLRYAAYNC VAIDTDMSPW EE (3-213 aa encoded by BC019105)
E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase HECTD3; HECT domain containing E3 ubiquitin protein ligase 3; HECT domain-containing protein 3; HECT-type E3 ubiquitin transferase HECTD3; probable E3 ubiquitin-protein ligase HECTD3
基因别名: 1700064K09Rik; AI467540; AW743312; HECTD3
UniProt ID: (Human) Q5T447, (Mouse) Q3U487
Entrez Gene ID: (Human) 79654, (Mouse) 76608