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Invitrogen
HECW1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-52457
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: STEPESAQIQ DSPMNNLMES GSGEPRSEAP ESSESWKPEQ LGEGSVPDGP GNQSIELSRP AEEAAVITEA GDQGMVSVGP EGAGELLAQV QKDIQPAPSA EELAEQLDLG EEASALLLED GEAPAS
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 44%.
靶标信息
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HECT type E3 ubiquitin ligase; HECT-type E3 ubiquitin transferase HECW1; KIAA0322; NEDD4-like ubiquitin-protein ligase 1; unnamed protein product
基因别名: NEDL1
UniProt ID: (Human) Q76N89
Entrez Gene ID: (Human) 23072
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
