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Invitrogen
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Immunogen sequence: GQVVSFGHGP SDTSKPTHPE ALTENFDISC LISAEDLVDV QVKHIFAGTY ANFVTTHQDT SSTRAPGKTL PEISRISQSM
Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 59%.
HERC6 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).
仅用于科研。不用于诊断过程。未经明确授权不得转售。