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Invitrogen
HERV-FRD Polyclonal Antibody
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产品信息
PA5-76129
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein of human HERV-FRD.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties. HERV-FRD can make pseudotypes with MLV, HIV-1 or SIV-1 virions and confer infectivity.Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).[supplied by OMIM].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Endogenous retrovirus group FRD member 1; endogenous retrovirus group FRD, member 1; envelope glycoprotein syncytin-A; envelope glycoprotein syncytin-B; Envelope polyprotein; FLJ41944; FLJ90611; HERV-FRD; HERV-FRD provirus ancestral Env polyprotein; HERV-FRD_6p24.1 provirus ancestral Env polyprotein; MGC87585; placenta-specific/fusogenic; Synb; syncytin 2; Syncytin-2; Syncytin-B; Syncytin2
基因别名: D930020E02Rik; envFRD; ERVFRD-1; ERVFRDE1; GLLL6191; Gm52; HERV-FRD; HERV-W/FRD; Synb; syncytin-B; UNQ6191; UNQ6191/PRO20218
UniProt ID: (Human) P60508, (Mouse) Q8BI41
Entrez Gene ID: (Human) 405754, (Rat) 288602, (Mouse) 239167
