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Invitrogen
HLA-DR/DP/DQ Monoclonal Antibody (CR3/43)
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产品信息
MA1-25910
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
CR3/43
抗原
Membrane rich fraction of human breast carcinoma.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C, do not freeze
运输条件
Wet ice
RRID
产品详细信息
MA1-25910 detects HLA DR + DP + DQ from human samples.
MA1-25910 has been successfully used in immunohistochemistry (frozen), and immunohistochemistry (paraffin) procedures.
The MA1-25910 immunogen is a membrane rich fraction of human breast carcinoma.
靶标信息
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They therefore have a critical role in the initiation of the immune response.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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