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Proteintech
HMG20A Monoclonal Antibody (1B10F12)
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产品信息
66676-1-IG
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1B10F12
抗原
HMG20A Fusion Protein Ag2718 (1-347 aa encoded by BC021959)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MENLMTSST LPPLFADEDG SKESNDLATT GLNHPEVPYS SGATSSTNNP EFVEDLSQGQ LLQSESSNAA EGNEQRHEDE QRSKRGGWSK GRKRKKPLRD SNAPKSPLTG YVRFMNERRE QLRAKRPEVP FPEITRMLGN EWSKLPPEEK QRYLDEADRD KERYMKELEQ YQKTEAYKVF SRKTQDRQKG KSHRQDAARQ ATHDHEKETE VKERSVFDIP IFTEEFLNHS KAREAELRQL RKSNMEFEER NAALQKHVES MRTAVEKLEV DVIQERSRNT VLQQHLETLR QVLTSSFASM PLPGSGETPT VDTIDSYMNR LHSIILANPQ DNENFIATVR EVVNRLDR (1-347 aa encoded by BC021959)
靶标信息
Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ10739; High mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; iBRAF; Inhibitor of BRAF35
基因别名: 1200004E06Rik; 5730490E10Rik; HMG20A; HMGX1; HMGXB1; Ibraf
UniProt ID: (Human) Q9NP66, (Mouse) Q9DC33
Entrez Gene ID: (Human) 10363, (Mouse) 66867
