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HOMER1 Polyclonal Antibody
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HOMER1 Antibody (OSH00002W-100UL) in IHC (P)
IHC-P on paraffin sections of rat spinal cord. The animal was perfused using Autoperfuser at a pressure of 110 mmHg with 300 mL 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instruct... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
OSH00002W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from the internal region of human HOMER1 (Home1, Homer protein homolog 1, SYN47) conjugated to an immunogenic carrier protein was used as the antigen
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous with the corresponding sequence in mouse, rat and monkey.
Specificity of this antibody: Homer1.
靶标信息
HOMER1 is a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: anchor protein; EVH1/WH1-domain protein; homer homolog 1; homer scaffolding protein 1; homer, neuronal immediate early gene, 1; homer-1; immediate early gene protein Homer1A; PSD-Zip45; scaffold protein; unnamed protein product; VASP/Ena-related gene up-regulated during seizure and LTP 1
基因别名: HOMER; homer-1; HOMER1A; HOMER1B; HOMER1C; HOMER1F; PSD-Zip45; SYN47; Ves-1; Vesl-1
UniProt ID: (Human) Q86YM7, (Mouse) Q9Z2Y3, (Rat) Q9Z214
Entrez Gene ID: (Human) 9456, (Mouse) 26556, (Rat) 29546
protein binding
G-protein coupled glutamate receptor binding
signaling adaptor activity
ion channel binding
receptor binding
type 5 metabotropic glutamate receptor binding
identical protein binding
macromolecular complex binding
binding, bridging
scaffold protein binding
structural constituent of postsynapse
skeletal muscle contraction
G-protein coupled glutamate receptor signaling pathway
memory
protein localization to synapse
response to cocaine
behavioral response to cocaine
skeletal muscle fiber development
protein tetramerization
response to calcium ion
positive regulation of calcium ion transport
regulation of synaptic transmission, glutamatergic
regulation of calcium ion import
postsynapse organization
regulation of dendritic spine maintenance
regulation of store-operated calcium entry
phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
positive regulation of signal transduction
circadian rhythm
response to nicotine
cellular response to L-glutamate
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
