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This target displays homology in the following species: Cow: 85%; Dog: 85%; Guinea Pig: 85%; Horse: 91%; Human: 85%; Mouse: 100%; Rabbit: 85%; Rat: 100%
HOXD3 (homeobox D3) belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that remove the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. HOXD3 may play a role in the regulation of cell adhesion processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: homeo box D3; homeo box D4; Homeobox protein Hox-4.1; Homeobox protein Hox-D3; Homeobox protein MH-19; MGC10470
基因别名: Hox-4.1; Hox-5.5; Hoxd-3; Hoxd3
UniProt ID: (Mouse) P09027
Entrez Gene ID: (Mouse) 15434