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Proteintech
HSF4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
22883-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
HSF4 Fusion Protein Ag18935 (369-492 aa encoded by BC153061)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.38 mg/mL
规格
57 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
This antibody is specific to human HSF4.
Immunogen sequence: DRSPESLLP PMLLQPPQES VEPAGPLDVL GPSLQGREWT LMDLDMELSL MQPLVPERGE PELAVKGLNS PSPGKDPTLG APLLLDVQAA LGGPALGLPG ALTIYSTPES RTASYLGPEA SPSP (369-492 aa encoded by B C153061)
靶标信息
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AT-HSFB1; ATHSF4; binds heat shock DNA elements; cataract; DNA binding protein; heat shock factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner; unnamed protein product
基因别名: CTM; CTRCT5; HSF 4; HSTF 4; HSTF4; ldis1; mHSF4
UniProt ID: (Human) Q9ULV5, (Mouse) Q9R0L1
Entrez Gene ID: (Human) 3299, (Rat) 291960, (Mouse) 26386
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein phosphatase binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
eye development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
visual perception
positive regulation of cell proliferation
camera-type eye development
positive regulation of cell differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cell development
lens fiber cell differentiation
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