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Invitrogen
HSP105 Polyclonal Antibody
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HSP105 Antibody (PA5-77793) in IHC
Immunohistochemistry analysis of HSPH1 in mouse back skin. Samples were incubated with HSPH1 polyclonal antibody (Product # PA5-77793) using a dilution of 1:100 (1 hour at RT) and followed by FITC Goat Anti-Rabbit (green) at a dilution of 1:50 (1 hour at RT).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-77793
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Hamster,
Human,
Mouse,
Sheep,
Rhesus monkey,
Rat,
Shark,
Yeast
已发表种属
Bovine
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide derived from the sequence of hamster HSP110; sequence identical to human and mouse (C-KDEKYNHIDES)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunohistochemistry samples may be prepared using Bouin's Fixative solution.
1 µg/mL of PA5-77793 was sufficient for detection of HSP110 in 10 µg of human cell line mixed lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.|Detects approximately 110kDa.
靶标信息
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 42 degrees C-HSP; Antigen NY-CO-25; heat shock 105kDa; heat shock 105kDa/110kDa protein 1; Heat shock 110 kDa protein; Heat shock protein; Heat shock protein 105 kDa; heat shock protein 110; Heat shock protein family H member 1; heat shock protein, 105 kDa; Heat shock-related 100 kDa protein E7I; heat-shock protein 110 kDa; HSP; HSP-E7I; HSP105 42 C-HSP; NY CO 25
基因别名: 105kDa; AI790491; hsp-E7I; HSP105; HSP110; hsp110/105; HSPH1; I79_002075; KIAA0201
UniProt ID: (Bovine) Q0IIM3, (Mouse) Q61699, (Rat) Q66HA8, (Chinese hamster) Q60446
regulation of catalytic activity
chaperone mediated protein folding requiring cofactor
response to unfolded protein
negative regulation of neuron apoptotic process
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of NK T cell activation
positive regulation of protein tyrosine kinase activity
regulation of microtubule cytoskeleton organization
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of p38MAPK cascade
negative regulation of apoptotic signaling pathway
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