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Invitrogen
HSP60 Monoclonal Antibody (A57-B9)
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HSP60 Antibody (MA3-023) in ICC/IF
PloS one 2014 -
Figure 1 Peroxisomes are translocated into the Chlamydia inclusion during infection. A- HeLa cells were infected with C. trachomatis L2 for 20 h. The inclusion membrane was labeled with an anti-CT813 antibody (green), peroxisomes with an anti-ALDP antibody (red) and bacterial and nuclear DNA with Hoechst (Blue). A single ApoTome x-y section is shown in the central image. The z-x projection on the top shows ... View More
产品信息
MA3-023
应用
建议稀释比
已发表文章
产品规格
种属反应
Bacteria
已发表种属
Bacteria,
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
A57-B9
抗原
Recombinant Chlamydia trachomatis HSP60 protein.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA3-023 detects heat shock protein 60 kDa (HSP60) from bacteria. This antibody detects all three species of Chlamydia HSP60 with minimal cross-reactivity with Borrelia burgdorferi HSP60. MA3-023 does not react with E. coli GroEL.
MA3-023 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects a single ~60 kDa band representing HSP60 from C. trachomatis lysate.
The MA3-023 immunogen is recombinant Chlamydia trachomatis HSP60. Epitope mapping studies suggest that this antibody binds to a linear sequence of Chlamydia HSP60 amino acids 517-522.
靶标信息
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
