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Invitrogen
HSP60 Monoclonal Antibody (A57-E4)
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产品信息
MA3-022
产品规格
种属反应
Bacteria
已发表种属
Bacteria
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
A57-E4
抗原
Recombinant Chlamydia trachomatis HSP60.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA3-022 detects heat shock protein 60 kDa (HSP60) from bacteria. This antibody detects HSP60 from all three species of Chlamydia, Escherichia coli (GroEL), Salmonella typhimurium, Neisseria gonorrhoeae and Coxiella burnetti. MA3-022 does not cross react with HeLa cell HSP60.
MA3-022 has been successfully used in Western blot procedures. By Western blot, this antibody detects a single ~60 kDa protein representing HSP60 from C. trachomatis lysate.
The MA3-022 immunogen is recombinant Chlamydia trachomatis HSP60. Epitope mapping studies suggest that this antibody binds to a linear sequence of 6 amino acids of Chlamydia HSP60 amino acids 117-122.
靶标信息
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
