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Proteintech
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This antibody was raised against the C-terminal region of human HSPA6 and it may cross-react with HSPA1 (HSP70), HSPA1L and HSPA2.
Immunogen sequence: DFYTSITRA RFEELCSDLF RSTLEPVEKA LRDAKLDKAQ IHDVVLVGGS TRIPKVQKLL QDFFNGKELN KSINPDEAVA YGAAVQAAVL MGDKCEKVQD LLLLDVAPLS LGLETAGGVM TTLIQRNATI PTKQTQTFTT YSDNQPGVFI QVYEGERAMT KDNNLLGRFE LSGIPPAPRG VPQIEVTFDI DANGILSVTA TDRSTGKANK ITITNDKGRL SKEEVERMVH EAEQYKAEDE AQRDRVAAKN SLEAHVFHVK GSLQEESLRD KIPEEDRRKM QDKCREVLAW LEHNQLAEKE EYEHQKRELE QICRPIFSRL YGGPGVPGGS SCGTQARQGD PSTGPIIEEV D (294-643 aa encoded by BC035665)
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Heat shock 70 kDa protein 6; Heat shock 70 kDa protein B'; heat shock 70kD protein 6 (HSP70B'); heat shock 70kDa protein 6 (HSP70B'); Heat shock protein; Heat shock protein family A member 6; HSP
基因别名: HSP70B'; HSPA6
UniProt ID: (Human) P17066
Entrez Gene ID: (Human) 3310