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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: EAWRPRWAF NWDTKDIYRQ RSRALVQAQH PDWPAPQVEA VAQDQFQGAA RAWMAGTLQL GRALRPRGLW GFYGFPDCYN YDFLSPNYTG QCPSGIRAQN DQLGWLWGQS RALYPSIYMP AVLEGTGKSQ MYVQHRVAEA FRVAVAAGDP NLPVLPYVQI FYDTTNHFLP LDELEHSLGE SAAQGAAGVV LWVSWENTRT KESCQAIKEY MDTTLGPFIL NVTSGALLCS QALCSGHGRC VRRTSHPKAL LLLNPASFSI QLTPGGGPLS LRGALSLEDQ AQMAVEFKCR CYPGWQAPWC ERKSMW (131-435 aa encoded by BC035695)
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Hyal-1; Hyaluronidase; hyaluronidase 1; Hyaluronidase-1; Hyaluronoglucosaminidase-1; LuCa-1; Lung carcinoma protein 1
基因别名: Hya1; Hyal-1; HYAL1; LUCA1
UniProt ID: (Mouse) Q91ZJ9
Entrez Gene ID: (Mouse) 15586