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Bioss

Heme Oxygenase 1, Heme Oxygenase 2 Polyclonal Antibody

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说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
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产品信息

BS-2075R

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:300
-

免疫组化（石蜡） (IHC (P))

1:500
-

免疫组化（冰冻） (IHC (F))

1:100-1:500
-

免疫细胞化学 (ICC/IF)

1:50-1:200
-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000
-
产品规格

种属反应

Chicken, Human, Mouse, Pig, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human Heme Oxygenase 1.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

100 µg

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

Heme oxygenase cleaves the heme ring at the alpha methane bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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Cite this product

生物信息学

蛋白别名: heat shock protein 32; heat shock protein, 32-kD; heme oxygenase; heme oxygenase (decycling) 1; heme oxygenase (decycling) 2; heme oxygenase (decyclizing) 1; heme oxygenase-2 (EC 1.14.99.3); hemoxygenase; HMOX1; HMOX2; HO-1; HO2; P32 protein; unnamed protein product

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基因别名: bK286B10; D8Wsu38e; Hemox; Heox; HEOXG; Hmox; HMOX1D; HO-1; HO-2; HO1; HO2; HSP32

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UniProt ID: (Pig) P32394, (Human) P09601, (Chicken) P14791, (Human) P30519, (Rat) P06762, (Mouse) P14901, (Mouse) O70252, (Rat) P23711

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Entrez Gene ID: (Pig) 445512, (Human) 3162, (Chicken) 396287, (Chicken) 416663, (Human) 3163, (Pig) 396622, (Rat) 24451, (Mouse) 15368, (Mouse) 15369, (Rat) 79239

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功能
heme oxygenase (decyclizing) activity heme binding identical protein binding protein homodimerization activity metal ion binding structural molecule activity protein binding enzyme binding phospholipase D activity arachidonic acid omega-hydroxylase activity oxygenase
参与通路
wound healing involved in inflammatory response heme oxidation cellular iron ion homeostasis apoptotic process response to oxidative stress erythrocyte homeostasis regulation of transcription from RNA polymerase II promoter in response to iron response to nicotine heme catabolic process heme metabolic process positive regulation of I-kappaB kinase/NF-kappaB signaling negative regulation by host of viral transcription positive regulation of smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation iron ion homeostasis cellular response to arsenic-containing substance cellular response to cadmium ion negative regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of viral life cycle angiogenesis endothelial cell proliferation negative regulation of leukocyte migration regulation of transcription from RNA polymerase II promoter smooth muscle hyperplasia positive regulation of chemokine production low-density lipoprotein particle clearance cellular response to heat intracellular signal transduction response to hydrogen peroxide regulation of angiogenesis positive regulation of angiogenesis multicellular organismal iron ion homeostasis positive regulation of cell migration involved in sprouting angiogenesis negative regulation of ferroptosis negative regulation of cytokine production involved in inflammatory response positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis response to hypoxia phospholipid metabolic process small GTPase mediated signal transduction regulation of blood pressure negative regulation of cell proliferation intrinsic apoptotic signaling pathway in response to DNA damage response to xenobiotic stimulus negative regulation of muscle cell apoptotic process positive regulation of macroautophagy negative regulation of macroautophagy cellular response to nutrient negative regulation of mast cell cytokine production positive regulation of apoptotic process negative regulation of mast cell degranulation negative regulation of neuron apoptotic process response to estrogen cellular response to cisplatin liver regeneration negative regulation of epithelial cell apoptotic process response to arachidonate response to 3-methylcholanthrene negative regulation of vascular smooth muscle cell proliferation cellular response to iron ion starvation
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