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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total IBTK.
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IBtk; Inhibitor of Bruton tyrosine kinase; RP1-93K22.1
基因别名: BTKI; IBTK; KIAA1417
Entrez Gene ID: (Human) 25998