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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PLTALNTDPAG AVNKQGDSIL CR
Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.
ID4 is transcription factors containing a basic helix-loop-helix (bHLH) motif regulate expression of tissue-specific genes in a number of mammalian and insect systems. DNA-binding activity of the bHLH proteins is dependent on formation of homo- and/or heterodimers. Dominant-negative HLH proteins encoded by Id-related genes, such as ID4, also contain the HLH-dimerization domain but lack the DNA-binding basic domain. Consequently, Id proteins inhibit binding to DNA and transcriptional transactivation by heterodimerization with bHLH proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: class B basic helix-loop-helix protein 27; inhibitor of differentiation 4; inhibitor of DNA binding 4, dominant negative helix-loop-helix protein; inhibitor of DNA binding 4, HLH protein
基因别名: bHLHb27; IDB4
UniProt ID: (Human) P47928
Entrez Gene ID: (Human) 3400