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Proteintech
IDH2 Recombinant Rabbit Monoclonal Antibody (1B1)
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产品信息
82117-1-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
Mammalian cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1B1
抗原
Recombinant protein
偶联物
形式
Liquid
纯化类型
Protein A
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: TQKYSVAVKC ATITPDEARV EEFKLKKMWK SPNGTIRNIL GGTVFREPII CKNIPRLVPG WTKPITIGRH AHGDQYKATD FVADRAGTFK MVFTPKDGSG VKEWEVYNFP AGGVGMGMYN TDESISGFAH SCFQYAIQKK WPLYMSTKNT ILKAYDGRFK DIFQEIFDKH YKTDFDKNKI WYEHRLIDDM VAQVLKSSGG FVWACKNYDG DVQSDILAQG FGSLGLMTSV LVCPDGKTIE AEAAHGTVTR HYREHQKGRP TSTNPIASIF AWTRGLEHRG KLDGNQDLIR FAQMLEKVCV ETVESGAMTK DLAGCIHGLS NVKLNEHFLN TTDFLDTIKS NLDRALGRQ
靶标信息
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NADas the electron acceptor and the other NADP. Five isocitrate dehydrogenases have been reported: three NAD-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ICD-M; IDH; IDP; isocitrate dehydrogenase 2 (NADP+), mitochondrial; Isocitrate dehydrogenase [NADP], mitochondrial; NADP(+)-specific ICDH; NADP+-specific ICDH; NADP+-specific isocitrate dehydrogenase; Oxalosuccinate decarboxylase
基因别名: D2HGA2; E430004F23; ICD-M; IDH; Idh-2; IDH2; IDHM; IDP; IDPM; mNADP-IDH
UniProt ID: (Human) P48735, (Mouse) Q9EQK1, (Rat) P56574
Entrez Gene ID: (Human) 3418, (Mouse) 269951, (Rat) 361596
