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IFT122 Monoclonal Antibody (3E11)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00055764-M03
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E11
抗原
IFT122 (NP_443711, 1194 a.a. approximately 1291 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.3 mg/mL
规格
50 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: SIGDEDPFTA KLSFEQGGSE FVPVVVSRLV LRSMSRRDVL IKRWPPPLRW QYFRSLLPDA SITMCPSCFQ MFHSEDYELL VLQHGCCPYC RRCKDDPG
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: intraflagellar transport 122 homolog; unnamed protein product; WD repeat domain 10; WD repeat protein; WD repeat-containing protein 10; WD repeat-containing protein 140
基因别名: CED; CED1; CFAP80; FAP80; SPG; WDR10; WDR10p; WDR140
UniProt ID: (Human) Q9HBG6
Entrez Gene ID: (Human) 55764
neural tube closure
embryonic body morphogenesis
spinal cord dorsal/ventral patterning
embryonic heart tube development
embryonic forelimb morphogenesis
intracellular signal transduction
intraciliary anterograde transport
intraciliary retrograde transport
intraciliary transport
negative regulation of smoothened signaling pathway
camera-type eye morphogenesis
limb development
cilium morphogenesis
embryonic heart tube left/right pattern formation
protein localization to cilium
establishment of protein localization to organelle
protein localization to nonmotile primary cilium
non-motile cilium assembly
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
