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Abnova
IFT57 Monoclonal Antibody (1G8)
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产品信息
H00055081-M02
产品规格
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1G8
抗原
IFT57 (NP_060480, 214 a.a. approximately 312 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: QTYHLDMNET AKQEDILEST TDAAEWSLEV ERVLPQLKVT IRTDNKDWRI HVDQMHQHRS GIESALKETK GFLDKLHNEI TRTLEKISSR EKYINNQLE
靶标信息
HIPPI is required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway. Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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