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Proteintech
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Immunogen sequence: AACVCSYDDD ADELSVFCSS RNLTRLPDGV PGGTQALWLD GNNLSSVPPA AFQNLSSLGF LNLQGGQLGS LEPQALLGLE NLCHLHLERN QLRSLALGTF AHTPALASLG LSNNRLSRLE DGLFEGLGSL WDLNLGWNSL AVLPDAAFRG LGSLRELVLA GNRLAYLQPA LFSGLAELRE LDLSRNALRA IKANVFVQLP RLQKLYLDRN LIAAVAPGAF LGLKALRWLD LSHNRVAGLL EDTFPGLLGL RVLRLSHNAI ASLRPRTFKD LHFLEELQLG HNRIRQLAER SFEGLGQLEV LTLDHNQLQE VKAGAFLGLT NMAVMNLSGN CLRNLP
The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ALS; insulin-like growth factor binding protein complex acid labile chain; insulin-like growth factor binding protein, acid labile subunit; Insulin-like growth factor-binding protein complex acid labile subunit
基因别名: ACLSD; ALS; IGFALS
UniProt ID: (Human) P35858
Entrez Gene ID: (Human) 3483