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Invitrogen
IGFBP2 Polyclonal Antibody
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产品信息
PA1-21991
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Bovine IGFBP 2 purified by immunoaffinity and HPLC chromatographies from conditioned medium of Madin Darby Bovine Kidney cells
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-21991 detects IGFBP2 in bovine, hamster, equine, goat, human, mouse and non-human primate samples. This antibody may show a slight cross reactivity with IGFBP 1, 3, 4, & 5.
PA1-21991 has been successfully used in Immunoprecipitation and Western Blot procedures.
The PA1-21991 immunogen is bovine IGFBP 2 purified by immunoaffinity and HPLC chromatographies from conditioned medium of Madin Darby Bovine Kidney cells.
靶标信息
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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