Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
IL-13 Monoclonal Antibody (JES10-5A2)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
OMA1-03356
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Rat
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
JES10-5A2
抗原
Purified recombinant human IL-13.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
OMA1-03356 detects IL-13 from human samples.
OMA1-03356 has been successfully used in ELISA, Neutralizing, Western blot and immunohistochemistry (paraffin embedded) procedures. Further dilutions should be made in buffered solution with carrier protein, such as PBS with 1.0% BSA. The addition of a preservative such as 0.1% sodium azide is also recommended.
The OMA1-03356 immunogen is purified recombinant human IL-13.
靶标信息
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
