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PA5-34660 targets IL18 in ELISA, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-34660 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 179 of IL18 (Uniprot ID#Q14116).
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein can specifically interact with this cytokine, and thus negatively regulate its biological activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。