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OriGene
IL12RB2 Polyclonal Antibody
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IL12RB2 Antibody (TA590087) in WB
Western blot analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Cat # PS100001, Left lane) or pCMV6-ENTRY IL12RB2 (Cat # RC211143, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and blotted with anti-IL12(Cat # TA590087). Positive lysates [LY400597] (100 µg) and [LC400597] (20 µg) can be purchased separately from OriGene.
产品信息
TA590087
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
偶联物
形式
Liquid
浓度
1.04818 mg/mL
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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