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Proteintech
IL2RG Polyclonal Antibody
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产品信息
11409-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IL2RG Fusion Protein Ag1911 (1-369 aa encoded by BC014972)
偶联物
形式
Liquid
浓度
0.14 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MLKPSLPFT SLLFLQLPLL GVGLNTTILT PNGNEDTTAD FFLTTMPTDS LSVSTLPLPE VQCFVFNVEY MNCTWNSSSE PQPTNLTLHY WYKNSDNDKV QKCSHYLFSE EITSGCQLQK KEIHLYQTFV VQLQDPREPR RQATQMLKLQ NLVIPWAPEN LTLHKLSESQ LELNWNNRFL NHCLEHLVQY RTDWDHSWTE QSVDYRHKFS LPSVDGQKRY TFRVRSRFNP LCGSAQHWSE WSHPIHWGSN TSKENPFLFA LEAVVISVGS MGLIISLLCV YFWLERTMPR IPTLKNLEDL VTEYHGNFSA WSGVSKGLAE SLQPDYSERL CLVSEIPPKG GALGEGPGAS PCNQHSPYWA PPCYTLKPET (1-369 aa encoded by BC014972)
靶标信息
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD132; CD132 antigen; common cytokine receptor gamma chain; Cytokine receptor common subunit gamma; gammaC; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL2R gamma; interleukin 2 receptor, gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); Interleukin-2 receptor subunit gamma; p64
基因别名: [g]c; Ab2-183; CD132; CIDX; gamma(c); gc; IL-2RG; IL2RG; IMD4; P64; SCIDX; SCIDX1
UniProt ID: (Human) P31785, (Mouse) P34902
Entrez Gene ID: (Human) 3561, (Rat) 140924, (Mouse) 16186
MAPK cascade
immune response
signal transduction
viral process
interleukin-4-mediated signaling pathway
interleukin-2-mediated signaling pathway
interleukin-7-mediated signaling pathway
positive regulation of GTPase activity
regulation of gene expression
positive regulation of gene expression
cytokine-mediated signaling pathway
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
positive regulation of T cell differentiation in thymus
positive regulation of B cell differentiation
positive regulation of lymphocyte differentiation
