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Invitrogen
INHBB Polyclonal Antibody
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INHBB Antibody (PA5-81202) in ICC/IF
Immunofluorescence staining of INHBB in A431 cells. Cells were fixed with 4% PFA, blocked with 10% serum. Then incubated with INHBB Polyclonal Antibody (Product # PA5-81202) (1:5000)(Figure A), incubated with INHBB Polyclonal Antibody (Product # PA5-81202) and antigen (Figure B) at 4° C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
产品信息
PA5-81202
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the N-terminus of the Human Inhibin beta B/INHBB
偶联物
形式
Liquid
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Wet ice
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human Inhibin beta B.
靶标信息
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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