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Proteintech
INO80 Polyclonal Antibody
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产品信息
24819-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
INO80 Fusion Protein Ag20309 (1217-1556 aa encoded by BC146785)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: KQVTVYRLI CKGTIEERIL QRAKEKSEIQ RMVISGGNFK PDTLKPKEVV SLLLDDEELE KKLRLRQEEK RQQEETNRVK ERKRKREKYA EKKKKEDELD GKRRKEGVNL VIPFVPSADN SNLSADGDDS FISVDSAMPS PFSEISISSE LHTGSIPLDE SSSDMLVIVD DPASSAPQSR ATNSPASITG SVSDTVNGIS IQEMPAAGRG HSARSRGRPK GSGSTAKGAG KGRSRKSTAG SAAAMAGAKA GAAAASAAAY AAYGYNVSKG ISASSPLQTS LVRPAGLADF GPSSASSPLS SPLSKGNNVP GNPKNLHMTS SLAPDSLVRK QGKGTNPSGG R (1217-1556 aa encoded by BC146785)
靶标信息
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Chromatin-remodeling ATPase INO80; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; hINO80; homolog of yeast INO80; INO80 complex subunit A; INO80 homolog; putative DNA helicase INO80 complex homolog 1
基因别名: hINO80; INO80; INO80A; INOC1; KIAA1259
UniProt ID: (Human) Q9ULG1
Entrez Gene ID: (Human) 54617
mitotic sister chromatid segregation
double-strand break repair via homologous recombination
double-strand break repair
chromatin remodeling
transcription, DNA-templated
positive regulation of nuclear cell cycle DNA replication
positive regulation of cell growth
DNA duplex unwinding
cellular response to UV
positive regulation of transcription from RNA polymerase II promoter
spindle assembly
cell division
UV-damage excision repair
cellular response to ionizing radiation
regulation of G1/S transition of mitotic cell cycle
