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Proteintech
INTS9 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
11657-1-AP
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
INTS9 Fusion Protein Ag2226 (309-658 aa encoded by BC025267)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.16 mg/mL
规格
24 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LECLYQYID SAGLSSVPLY FISPVANSSL EFSQIFAEWL CHNKQSKVYL PEPPFPHAEL IQTNKLKHYP SIHGDFSNDF RQPCVVFTGH PSLRFGDVVH FMELWGKSSL NTVIFTEPDF SYLEALAPYQ PLAMKCIYCP IDTRLNFIQV SKLLKEVQPL HVVCPEQYTQ PPPAQSHRMD LMIDCQPPAM SYRRAEVLAL PFKRRYEKIE IMPELADSLV PMEIKPGISL ATVSAVLHTK DNKHLLQPPP RPAQPTSGKK RKRVSDDVPD CKVLKPLLSG SIPVEQFVQT LEKHGFSDIK VEDTAKGHIV LLQEAETLIQ IEEDSTHIIC DNDEMLRVRL RDLVLKFLQK F (309-658 aa encoded by BC025267)
靶标信息
INTS9 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A)and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1)and U2 (RNU2)(Baillat et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: protein related to CPSF subunits of 74 kDa; unnamed protein product
基因别名: CPSF2L; INT9; RC74
UniProt ID: (Human) Q9NV88
Entrez Gene ID: (Human) 55756
snRNA processing
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of transcription elongation from RNA polymerase II promoter
snRNA 3'-end processing
negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
regulation of cellular response to growth factor stimulus
RNA polymerase II transcription initiation surveillance
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