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Invitrogen
IQCG Polyclonal Antibody
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产品信息
PA5-84096
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: LDKLPMASTI TKIPSPLITE EGPNLPEIRH RGRFAVEFNK MQDLVFKKPT RQTIMTTETL KKIQIDRQFF SDVIADTIKE LQDSATYNSL LQA
Highest antigen sequence indentity to the following orthologs: Mouse - 47%, Rat - 42%.
靶标信息
IQCG is a protein coding gene. Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp434B227; Dynein regulatory complex protein 9; dynein regulatory complex subunit 9; IQ domain-containing protein G
基因别名: CFAP122; DRC9; IQCG
UniProt ID: (Human) Q9H095
Entrez Gene ID: (Human) 84223
