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Invitrogen
IQSEC2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-139945
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
规格
10 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: CSFEEYEKAQ NPAYFEGKPA SLDEGAMAGA RSHRLERGLP YGGSCGGGID GGGSSVTTSG EFSNDITELE DS
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 99%.
靶标信息
This gene encodes a guanine nucleotide exchange factor for the ARF family of small GTP-binding proteins. The encoded protein is a component of the postsynaptic density at excitatory synapses, and may play a critical role in cytoskeletal and synaptic organization through the activation of selected ARF substrates including ARF1 and ARF6. Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BRAG1b; IQsec2; BRAG1c; IQSec2; brefeldin A resistant Arf-guanine nucleotide exchange factor 1; brefeldin A resistant Arf-guanine nucleotide exchange factor 1b; brefeldin A resistant Arf-guanine nucleotide exchange factor 1c; IQ motif and Sec7 domain 2; IQsec2; unnamed protein product
基因别名: BRAG1; IQ-ArfGEF; MRX1; MRX18; MRX78; NEDXSB; XLID1
UniProt ID: (Human) Q5JU85
Entrez Gene ID: (Human) 23096
vesicle-mediated transport
regulation of ARF protein signal transduction
modulation of synaptic transmission
positive regulation of synapse assembly
positive regulation of synaptic transmission, glutamatergic
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
regulation of postsynaptic neurotransmitter receptor internalization
positive regulation of long term synaptic depression
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
