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Proteintech
IREB2 Polyclonal Antibody
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产品信息
23829-1-AP
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
IREB2 Fusion Protein Ag20653 (1-343 aa encoded by BC017880)
偶联物
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MDAPKAGYA FEYLIETLND SSHKKFFDVS KLGTKYDVLP YSIRVLLEAA VRNCDGFLMK KEDVMNILDW KTKQSNVEVP FFPARVLLQD FTGIPAMVDF AAMREAVKTL GGDPEKVHPA CPTDLTVDHS LQIDFSKCAI QNAPNPGGGD LQKAGKLSPL KVQPKKLPCR GQTTCRGSCD SGELGRNSGT FSSQIENTPI LCPFHLQPVP EPETVLKNQE VEFGRNRERL QFFKWSSRVF KNVAVIPPGT GMAHQINLEY LSRVVFEEKD LLFPDSVVGT DSHITMVNGL GILGWGVGGI ETEAVMLGLP VSLTLPEVVG CELTGSSNPF VTSIDVVLGI TKVS (1-343 aa encoded by BC017880)
靶标信息
Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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