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Immunogen sequence: GGQGAGNTGG LEPVHPASLP DSSLATSAPL CCTLCHERLE DTHFVQCPSV PSHKFCFPCS RQSIKQQGAS G
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Interferon regulatory factor 2-binding protein 2; IRF-2-binding protein 2
基因别名: E130305N23Rik; IRF-2BP2; IRF2BP2
UniProt ID: (Human) Q7Z5L9, (Mouse) E9Q1P8
Entrez Gene ID: (Human) 359948, (Mouse) 270110