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Invitrogen
ITGA4 Monoclonal Antibody (44H6), PE
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产品信息
MA1-80420
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
44H6
抗原
HOON pre-B leukemia cell line.
偶联物
PE
PE
PE
激发/发射光谱
565/576 nm
查看光谱
保存条件
4°C
产品详细信息
MA1-80420 detects CD49d (R-PE) in human sample types.
MA1-80420 has been successfully used in Flow cytometry applications.
The immunogen used to produce MA1-80420 is from HOON pre-B leukemia cell line.
Mouse anti Human CD49d monoclonal antibody, clone 44H6 recognizes human CD49d also known as integrin alpha-4 or VLA-4 subunit alpha.
靶标信息
The integrin alpha 4 (also known as CD49d and ITGA4) belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha and beta chains. Alpha4 chain associates with either beta1 or beta7 chain. It has been demonstrated that the putative ligand-binding sites of both integrin alpha4beta1 and alpha4beta7 is located on the alpha4 chain. These ligands included Madcam, VCAM, and fibronectin. Madcam is known as the principal ligand for integrin alpha4beta7. Recently it was also demonstrated that HIV-1 envelope can mimic Madcam by binding to and signaling though integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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