Search

  • 联系我们
  • 货号直购

Invitrogen

ITGA5/ITGB1 (Volociximab Biosimilar) Recombinant Rabbit Monoclonal Antibody (M200 (Volociximab))

查看其他9个ITGA5/ITGB1抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
证书
实验方案
问题与答案
技术支持
说明书
证书
实验方案
问题与答案
技术支持
说明书
证书
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}

产品信息

MA5-47968

应用
建议稀释比
已发表文章

免疫组化 (IHC)

Assay-dependent
-

免疫细胞化学 (ICC/IF)

10 µg/mL
-

流式细胞分析 (Flow)

10 µg/mL
-

酶联免疫吸附实验 (ELISA)

Assay-dependent
-

抑制试剂 (Inhibition)

Assay-dependent
-
产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG, kappa

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

M200 (Volociximab)

抗原

Heterodimeric alpha-5-Beta-1Fc fusion protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

规格

200 µg

纯化类型

Protein A

保存液

PBS

内含物

0.02% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_3074412

产品详细信息

Specificity: The antibody binds to human alpha-5Beta1 integrin with a Kd of 0.367 nM, an EC50 of 0.2 nM and an IC50 of 2.3 nM.

MA5-47968 is a chimeric antibody. The variable regions from one species have been grafted to the backbone of the other species.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: CD29; CD49 antigen-like family member E; CD49e; Fibronectin receptor subunit alpha; Fibronectin receptor subunit beta; fibronectin receptor, alpha polypeptide; fibronectin receptor, alpha subunit; Glycoprotein IIa; GPIIA; Integrin alpha-5; Integrin alpha-F; integrin beta 1; Integrin beta-1; integrin beta-1 subunit (cytoplasmic domain); Integrin beta1; integrin VLA-4 beta subunit; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITGA5/SLC9B1 fusion; surface glycoprotein receptor; unnamed protein product; very late activation protein 5, alpha subunit; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLA-5

查看更多 收起

基因别名: CD29; CD49e; FNRA; FNRB; GPIIA; ITGA5; ITGB1; MDF2; MSK12; VLA-5; VLA-BETA; VLA5A; VLAB

查看更多 收起

UniProt ID: (Human) P08648, (Human) P05556

查看更多 收起

Entrez Gene ID: (Human) 3678, (Human) 3688

查看更多 收起

功能
virus receptor activity receptor binding epidermal growth factor receptor binding platelet-derived growth factor receptor binding integrin binding calcium ion binding protein binding signaling receptor activity vascular endothelial growth factor receptor 2 binding metal ion binding cell adhesion molecule binding magnesium ion binding fibronectin binding protease binding actin binding coreceptor activity protein kinase binding C-X3-C chemokine binding laminin binding macromolecular complex binding cadherin binding protein heterodimerization activity collagen binding involved in cell-matrix adhesion integrin binding involved in cell-matrix adhesion protein tyrosine kinase binding
参与通路
angiogenesis formation of primary germ layer cell-substrate junction assembly cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion cell-matrix adhesion integrin-mediated signaling pathway female pregnancy memory tissue development positive regulation of cell-substrate adhesion response to muscle activity CD40 signaling pathway positive regulation of cell migration positive regulation of vascular endothelial growth factor receptor signaling pathway cell-substrate adhesion cell adhesion mediated by integrin cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion wound healing, spreading of epidermal cells endodermal cell differentiation regulation of angiogenesis viral entry into host cell cell-cell adhesion positive regulation of vascular endothelial growth factor signaling pathway positive regulation of sprouting angiogenesis negative regulation of anoikis G1/S transition of mitotic cell cycle establishment of mitotic spindle orientation in utero embryonic development cell migration involved in sprouting angiogenesis positive regulation of neuroblast proliferation phagocytosis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway neuroblast proliferation muscle organ development myoblast fusion cell proliferation germ cell migration visual learning regulation of collagen catabolic process positive regulation of fibroblast migration cell migration formation of radial glial scaffolds central nervous system neuron differentiation cell projection organization lamellipodium assembly B cell differentiation extracellular matrix organization neuron projection development receptor internalization negative regulation of Rho protein signal transduction maintenance of blood-brain barrier positive regulation of apoptotic process stress fiber assembly positive regulation of GTPase activity sarcomere organization myoblast differentiation negative regulation of neuron differentiation positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis negative regulation of vasoconstriction mesodermal cell differentiation myoblast fate specification axon extension dendrite morphogenesis regulation of developmental process modulation of synaptic transmission leukocyte tethering or rolling regulation of cell cycle positive regulation of protein kinase B signaling positive regulation of glutamate uptake involved in transmission of nerve impulse cardiac muscle cell differentiation cardiac muscle cell myoblast differentiation cardiac cell fate specification regulation of biological quality cellular response to low-density lipoprotein particle stimulus basement membrane organization positive regulation of wound healing regulation of spontaneous synaptic transmission reactive gliosis positive regulation of protein localization to plasma membrane regulation of synapse pruning
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持