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Invitrogen
ITGA7 Polyclonal Antibody
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ITGA7 Antibody (PA5-89699) in WB
Western blot analysis of ITGA7 in extracts of U-87MG cells. Samples were incubated with ITGA7 Polyclonal antibody (Product # PA5-89699) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-89699
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 880-1020 of human ITGA7 (NP_0021972)
偶联物
形式
Liquid
浓度
1.82 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: QVELEGGQGP GQKGLCSPRP NILHLDVDSR DRRRRELEPP EQQEPGERQE PSMSWWPVSS AEKKKNITLD CARGTANCVV FSCPLYSFDR AAVLHVWGRL WNSTFLEEYS AVKSLEVIVR ANITVKSSIK NLMLRDASTV I; Positive Samples: U-87MG; Cellular Location: Membrane, Single-pass type I membrane protein
靶标信息
Integrin alpha-7 is a protein that in humans is encoded by the ITGA7 gene. This gene is mapped to 12q13.2. The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: integrin alpha 7 chain; Integrin alpha-7; integrin, alpha 7
基因别名: ITGA7; UNQ406/PRO768
UniProt ID: (Human) Q13683
Entrez Gene ID: (Human) 3679
